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MEDICAL































             CAN CORONAVIRUSES




                   PRODUCE PSYCHIATRIC SYNDROMES?








                                                atypical pneumonia in Wuhan,  to  infect  CNS,  causing neurop-
            Coronaviruses and other similar     China,  which  were  subsequent-    sychiatric  syndromes    affecting
            infections in our brain: they can   ly  identifi ed  as  being  caused  by  cognitive,  affective,  behaviou-
            produce psychiatric sindromes?
                                                a novel coronavirus termed se-      ral,  and  perceptual domains.
                                                vere acute respiratory syndro-      As the pandemic of the disease has
                                                me  coronavirus 2 (SARS-CoV-2).     spread, there has been a growing
                                                There is the common idea that  recognition of the psychiatric impli-
            By Davide Perego                    the  fi rst  target  of  these  viruses  cations of the disease. In the me-
                                                is  the respiratory tract, althou-  antime the wider social impact of
            Coronaviruses are single-stran-     gh COVID-19 showed pleiotro-        the pandemic and the governmen-
            ded RNA viruses.  They belong to    pic effects, example dermatolo-     tal response, including physical di-
            a large family of respiratory viru-  gic and  vascular  damages.  It  is  stancing measures and quarantine,
            ses that can cause mild to mode-    interesting  take  into considera-  has interested all the people inde-
            rate  illnesses  from the  common   tion  also,  eventually psychiatric  pendent of the age and the status.
            cold disease to  respiratory syn-   and neuropsychiatric effects  of  Both  the infected and  non-in-
            dromes. In the past we known        SARS, MERS, and COVID-19.           fected population might be su-
            the  effects of  this type  of  viruses                                 sceptible as a result of pande-
            with severe acute respiratory syn-  Coronaviruses have also been  mic  period, such as widespread
            drome  (SARS),  starting  in 2002,   detected in both the brain and  anxiety, social isolation, stress  in
            and  Middle East  respiratory syn-  the  cerebrospinal  fl uid  of  indivi-  health-care workers and  other
            drome  (MERS),  starting  in 2012.  duals  with  seizures, encephalitis,  essential workers, and unemploy-
            On Dec 31, 2019,  WHO was           and encephalomyelitis.  In ge-      ment  and  fi nancial  diffi culties.
            made aware of several  cases  of    neral  viral  infections  are known  But over general effects,  expe-





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