Page 69 - Coespu 2020-2

Figure 1. (Evidence of the COVID-19 Virus Targeting the CNS: Tissue Distribution, Host–Virus Interaction,
and Proposed Neurotropic Mechanisms. Abdul Mannan Baig, Areeba Khaleeq Usman Ali, Hira Syeda. Pu-
blished online 2020 Mar 13. doi: 10.1021/acschemneuro.0c00122)
riences might be specifi c to in- patients admitted to hospital for in- and University of Brescia (Brescia),
dividuals who are infected with fection with SARS-CoV-2, 36% had University of Eastern Piedmont
the virus, such as concern about neurological features, mostly con- (Novara), and University of Sas-
the outcome of their illness, stig- sisting of mild symptoms such as sari, Sassari, have took considera-
ma, and amnesia or trauma- dizziness and headache, although tion images from 725 hospitalized
tic memories of severe illness. these symptoms might be mani- patients with confi rmed COVID-19
festations more of systemic illness infection between February 29 and
Neuropsychiatric consequences as than a specifi c neurological syn- April 4. Of these, 108 (15%) had
mental disorders that are the se- drome (Mao L Jin H Wang M et al. serious neurological symptoms
quelae of brain damage or disea- Neurologic manifestations of ho- and underwent brain or spine
se, can arise either thorough direct spitalized patients with coronavirus imaging. Most patients had brain
effects of infection of the CNS or disease 2019 in Wuhan, China. CT scans, while others had head
indirectly via an immune response JAMA Neurol. 2020; (published and neck CT imaging and brain
or medical therapy. A case series online April 10.). A study by Uni- MRI. Investigators found that 59%
from Wuhan found that among versity of Cincinnati researchers of patients reported an altered

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